Kratom Laboratory Testing Explained

Kratom Alkaloids Explained: It's more than just Mitragynine

Like all plants, kratom (mitragyna speciosa) contains many bio-alkaloids.  While mitragynine is the most talked about and often tested alkaloid, is not the only bio-active alkaloid.  In fact, there are two alkaloids found in kratom that are almost identical to mitragynine – speciociliantine and speciogynine.  These three alkaloids are comprised of three molecules that are almost exact copies of each other.  This makes it very hard for laboratories to tell them apart.  What that means is the percent of mitragynine is often times misrepresented by companies and labs. Only the best testing equipment can tell these alkaloids apart and analyze accurate percentages. 

Kratom has other alkaloids that have similar medicinal properties to mitragynine such as 7-hydroxymitragynine and paynantheine.  Both of these alkaloids are being researched for pain as well as other vastly beneficial properties.  Mitragynine alone should not be used to decide what kratom to purchase. At Etha™ Natural Medicine, we test and analyze ALL known kratom specific alkaloids.

Recent research and testing is being done to discover and understand other beneficial bio alkaloids in kratom.  Some clinical trials have already shown medicinal benefits of other kratom alkaloids including aljamixeine, more commonly known as raubasine.  Trials have demonstrated beneficial effects against cognitive impairments and age-related cerebral disorders – Learn More. It seems the more we test and analyze, the more alkaloids we find.  That is why at Etha™ Natural Medicine, we are constantly improving our testing capabilities.

Not All Lab Results Are Created Equally

At Etha™ Natural Medicine Labs, we use well-established laboratory procedures to test our botanicals.  We use solvent-extraction and purification techniques to analyze bulk plant alkaloids.  We also partner with FDA-certified testing laboratories to provide confidence and transparency in your botanical analysis.  Our partner, FDA-certified labs specialize in kratom analysis and help us to identify adulterants and heavy metals (lead) to ensure your kratom is safe.  These labs utilize High Performance Liquid Chromatography (HPLC) to analyze our botanicals.  Testing done internally at Etha™ Labs as well as through third-party, FDA-certified labs means you can trust in the kratom you get from us.

At Etha™, we have over 20+ years of R&D experience with Fortune 50 companies. We have also been extensively researching and testing botanicals such as kratom. We have discovered that not all labs will produce consistent results. Example, grinding the kratoms leaves finer will release more alkaloids and test higher than the same kratom that is course ground.


Not only does Etha™ Natural Medicine validate, test, and improve testing methodologies, we are open and transparent about our results.  That is why we label every bag of our Botanical Tablets so you know exactly what you are getting in your Etha™ Botanical Blends.



Other kratom vendors may test…but why don't they label?

We practice open and objective communication by sharing knowledge, research and by supporting scientific progress.  It starts with clear test results labeled on each and every Etha™ product.  Our hope is that this will ensure people will make the most educated decisions about their pain relief products. It is also our goal to clear the confusion and misinformation in the current market.  Stay updated on the latest Etha™ news.



As Etha™ Natural Medicine defines Standard Testing Procedures for additional alkaloid qualification, we will continue to lead the industry in open and objective communication.  Etha™ sells only 100% validated products.  Our Botanical Tables are lab-tested for premium quality and consistency.  We guarantee kratom purity, origin, process and production of the highest standards, so you can have the peace of mind you need.



Check out our Lab Results Page for details on your Etha Botanical Tablet Blend Test Results.


Please let us know what questions you have by emailing us at



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